Why the study?
Does preoperative withdrawal from alcohol reduce postoperative morbidity in alcohol abusers?
Does preoperative withdrawal from alcohol reduce postoperative morbidity in alcohol abusers?
Preoperative abstinence from alcohol for two months is theoretically proposed to reduce increased postoperative morbidity in alcohol abusers by allowing physiological functions to recover.
May support 2-month preoperative abstinence in alcohol abusers; leaves open confirmation in prospective trials.
Alcohol intake influences several physiological functions, including the haemostatic system, the cellular immune defence and the cardiac function, but to a different degree depending on the drinking habits. Restoration of these functions after withdrawal seems time related. The haemostatic imbalance normalizes within two or three weeks of soberness while the immune system requires about two months to recover. Recent studies have showed very increased postoperative morbidity after surgery in alcohol abusers, which may be explained by alcohol‐induced physiological dysfunctions. Theoretically, two months of abstinence before a surgical procedure would diminish the increased postoperative morbidity among alcohol abusers. However, further investigation is necessary to establish a clinical effect of preoperative withdrawal from alcohol.
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H. Tennesen (1992) studied this question.
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