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September 1, 2001PEDIATRICS

Breath-Holding Spells Associated With Significant Bradycardia: Successful Treatment With Permanent Pacemaker Implantation

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Why the study?

Does permanent pacemaker implantation prevent breath-holding spells in pediatric patients with severe bradycardia?

Population

10 pediatric patients with apparent breath-holding spells associated with severe bradycardia, onset of…

Design

Case_series

Follow-up

38 to 170 months (median: 65.5 months)

Authors

AKAmy M. KellyCPCo-burn J. PorterMMMichael D. McGoon

Discussion

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Overview

Pacemaker implantation was associated with spell improvement in most children; hypothesis-generating and requires prospective trials before practice change.

Structured PICO

Does permanent pacemaker implantation prevent breath-holding spells in pediatric patients with severe bradycardia?

P
Population
10 pediatric patients with apparent breath-holding spells associated with severe bradycardia (asystolic pauses of 1.7 to 24 seconds), onset of symptoms between ages 6 days and 12 months, who failed medication trials.
I
Intervention
Permanent ventricular demand pacemaker implantation (9 endocardial, 1 epicardial).
O
Outcome
Resolution of breath-holding spells and associated symptoms (syncope, seizures).

Permanent pacemaker implantation is a safe and effective treatment for children with severe, refractory pallid breath-holding spells associated with significant bradycardia or asystole.

Cite This Study

Kelly et al. (2001) studied this question.

synapsesocial.com/papers/6a762496c14fe0c475708fa9https://doi.org/10.1542/peds.108.3.698
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