The P2Y2 receptor mediates tissue factor expression in human coronary artery endothelial cells via Src/p38 and Rho/JNK pathways, highlighting a potential non-platelet mechanism for thrombosis after vascular injury.
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Suggests endothelial P2Y2 involvement in thrombosis; hypothesis-generating and should not yet change practice.
Ding et al. (2011) studied this question.
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