Microvascular Resistance Predicts Myocardial Salvage and Infarct Characteristics in ST‐Elevation Myocardial Infarction
Why the study?
Does the index of microvascular resistance predict myocardial salvage and infarct characteristics in patients with ST-elevation myocardial infarction?
Population
108 patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
Design
Cohort
Follow-up
3 months
Authors
Discussion
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Member takes
Implication
May refine post-PCI risk stratification in STEMI; hypothesis-generating and should not yet change practice.
Structured PICO
Does the index of microvascular resistance predict myocardial salvage and infarct characteristics in patients with ST-elevation myocardial infarction?
P
Population
108 patients with ST-elevation myocardial infarction (83% male) undergoing primary percutaneous coronary intervention
I
Intervention
Measurement of the index of microvascular resistance (IMR) using a pressure- and temperature-sensitive coronary guidewire at the end of primary percutaneous coronary intervention
O
Outcome
Myocardial salvage (calculated by subtracting infarct size from area at risk using cardiac MRI)surrogate
The index of microvascular resistance measured at the end of primary PCI is a strong predictor of myocardial salvage and infarct characteristics in STEMI patients.
Cite This Study
Payne et al. (2012) studied this question.