What question did this study set out to answer?

To identify radiological predictors of shunt responsiveness in patients with idiopathic normal pressure hydrocephalus and determine their diagnostic effectiveness.

November 26, 2022Acta NeurochirurgicaOpen Access

Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

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To identify radiological predictors of shunt responsiveness in patients with idiopathic normal pressure hydrocephalus and determine their diagnostic effectiveness.
Searched Embase, MEDLINE, Scopus, PubMed, Google Scholar, and JSTOR for studies assessing radiological predictors of shunt response in idiopathic normal pressure hydrocephalus.
Screened 301 full-text publications and included 28 studies evaluated with the ROBINS-1 tool, performing univariate meta-analyses on five eligible radiological features.
Of 26 identified radiological markers, only callosal angle and periventricular white matter changes significantly distinguished shunt responders from non-responders.
Both predictive markers demonstrated low diagnostic accuracy, yielding a diagnostic odds ratio of 1.88 for callosal angle and 1.01 for periventricular white matter changes, while markers such as disproportionately enlarged subarachnoid space and cerebral blood flow showed no significant differentiation.

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Implication

Systematic review and meta-analysis reveals weak predictive value of radiological markers for shunt response in normal pressure hydrocephalus, indicating imaging alone is insufficient.

Cite This Study

Thavarajasingam et al. (2022) studied this question.

synapsesocial.com/papers/6a762d3174b63c188eb22290 https://doi.org/10.1007/s00701-022-05402-8

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Implication

Systematic review and meta-analysis reveals weak predictive value of radiological markers for shunt response in normal pressure hydrocephalus, indicating imaging alone is insufficient.

Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

Key Points

Discussion

Implication

Cite This Study

Radiological predictors of shunt response in the diagnosis and treatment of idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis

Key Points

Discussion

Implication

Cite This Study

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