This article reviews the properties, activity, and indications of parenteral metronidazole for anaerobic infections.
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May guide parenteral metronidazole use in anaerobic infections; extends prior syntheses but leaves optimal dosing and resistance data open.
Within a few years of the introduction of oral metronidazole to treat parasitic infections, investigators began to notice its activity against anaerobic infections as well. Now a parenteral form of the drug is available for use in this expanded application. This article reviews the properties and activity of the drug and discusses its new indications.
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Edson et al. (1982) studied this question.
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