Why the study?
Menopause marks a transition in the aging process, prompting evaluation of sympathetic nervous system activity between normotensive premenopausal and postmenopausal women.
Does postmenopausal status alter sympathetic nervous system activity compared to premenopausal status in normotensive women?
Does postmenopausal status alter sympathetic nervous system activity compared to premenopausal status in normotensive women?
Postmenopausal women exhibit increased sympathetic nervous system activity and higher resting blood pressures compared to premenopausal women, suggesting a shift toward sympathetic dominance after menopause.
Suggests heightened sympathetic activity post-menopause; leaves open whether this alters CV risk or warrants intervention.
Background & Introduction: Menopause marks the period of many changes in women. The term menopause comprises as the stage of aging process which marks the transition from the reproductive phase of life to the post - reproductive phase. Aim & Objective: to compare the sympathetic nervous system activity using autonomic function tests in normotensive premenopausal women and postmenopausal women (had natural menopause). Materials & Method: The autonomic function tests in 30 premenopausal and 30 postmenopausal women were compared. Parameters under study were Height, Weight, BMI, Sympathetic function test like the blood pressure response to Orthostatic tolerance test, Sustained isometric hand grip test and Cold pressor test. Result: We found significant difference in BMI (P<0.05) and blood pressure during Orthostatic test, sustained isometric hand grip test and cold pressor test when compared between premenopausal and postmenopausal.
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Kumarchandra et al. (2022) studied this question.
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