Why the study?
Treatment of hypertension in the very elderly was historically controversial, while isolated systolic hypertension increases with age and predicts adverse cerebrovascular and renal outcomes.
Does treatment of hypertension improve outcomes in the very elderly with isolated systolic hypertension?
Does treatment of hypertension improve outcomes in the very elderly with isolated systolic hypertension?
Early detection and treatment of isolated systolic hypertension in the very elderly is important for preventing cerebrovascular and renal complications.
May support treating ISH in very elderly; leaves open optimal targets and agents for this population.
Globally, hypertension is a common problem in the elderly, and its prevalence increases with increasing age. Isolated systolic hypertension (ISH) subset is more common in the very elderly population, and as the population ages, its prevalence will rise more and more. In the past, treatment of hypertension (HT) in the very elderly was controversial and either no treatment or complications of treatment risk overweigh the benefits observed. The inclusion of elders in various clinical trials has demonstrated a better understanding and rational approach toward optimal management of HT. Systolic blood pressure (BP) is more important in predicting adverse cerebrovascular outcomes and decline in renal function in elderly patients with ISH. Early detection, protection of target organs, correction of high BP will develop, promote, and corroborate healthy aging.
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Meenaxi Sharda (2022) studied this question.
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