Key result
Pharmacologic therapy for isolated systolic hypertension in the elderly should be initiated at a low dose and increased slowly to minimize the risk of adverse effects.
Population
Elderly patients with isolated systolic hypertension (ISH)
Design
Review
Authors
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Requires cautious low-dose initiation in elderly ISH; leaves open optimal regimens pending dedicated RCTs.
Treatment of isolated systolic hypertension in the elderly provides clear benefits but requires careful initiation with low-dose pharmacologic therapy due to increased risk of adverse effects.
William H. Pentz (1999) conducted a review in Isolated systolic hypertension. Pharmacologic therapy was evaluated. Pharmacologic therapy for isolated systolic hypertension in the elderly should be initiated at a low dose and increased slowly to minimize the risk of adverse effects.
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