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January 1, 1998European Heart Journal

Changes in platelet size and count in unstable angina compared to stable angina or non-cardiac chest pain

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Why the study?

Do mean platelet volume and platelet count differ between patients with unstable angina, stable angina, and non-cardiac chest pain?

Population

981 patients presenting with stable angina, unstable angina, unstable angina requiring immediate…

Design

Cross-sectional

Authors

LPLuciano PizzulliUniversity of Bonn

Discussion

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Implication

Unstable angina-associated platelet changes are hypothesis-generating; prospective studies needed before diagnostic or prognostic use.

Structured PICO

Do mean platelet volume and platelet count differ between patients with unstable angina, stable angina, and non-cardiac chest pain?

P
Population
981 patients (734 men; 247 women) presenting with stable angina (n=688), unstable angina (n=108), unstable angina requiring immediate angioplasty (n=52), and non-cardiac chest pain (n=97).
C
Comparator
Non-cardiac chest pain and stable angina
O
Outcome
Mean platelet volume and platelet countsurrogate

Unstable angina is associated with a decrease in platelet count and an increase in platelet size, suggesting an increased platelet destruction rate and the presence of larger, more reactive platelets.

Cite This Study

Luciano Pizzulli (1998) studied this question.

synapsesocial.com/papers/6a763715cd662f67b2fbe180https://doi.org/10.1053/euhj.1997.0747
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