January 1, 2001Thrombosis and Haemostasis
Platelet Reactivity in Acute Coronary Syndromes: Evidence for Differences in Platelet Behaviour between Unstable Angina and Myocardial Infarction
Population
30 patients with acute coronary syndromes, consisting of unstable angina and acute myocardial infarction.
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Suggests distinct platelet phenotypes in UA versus MI; hypothesis-generating and requires prospective validation before any clinical use.
Structured PICO
P
Population
30 patients with acute coronary syndromes, consisting of unstable angina (n=15) and acute myocardial infarction (n=15).
O
Outcome
Differences in platelet behaviour markers including mean platelet volume (MPV), platelet count, and percentage of platelets expressing P-selectin.surrogate
Unstable angina and myocardial infarction exhibit fundamentally different platelet biology, with UA characterized by platelet consumption and increased size, whereas MI involves acute generalized platelet activation.
Cite This Study
Mathur et al. (2001) studied this question.