Why the study?
It remains uncertain whether elevated platelet indices are the cause or result of ACS, prompting evaluation of the correlation between mean platelet volume and platelet aggregation.
Does increased mean platelet volume correlate with increased platelet aggregation response in patients with acute coronary syndrome?
Population
50 patients with STE-ACS or NSTE-ACS
Comparison
Patients with MPV >9.1 fl vs MPV ≤9.1 fl
Design
Correlation study
Authors
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Elevated MPV in ACS does not indicate platelet hyperreactivity; leaves open whether it reflects marrow release of immature platelets after consumption.
Does increased mean platelet volume correlate with increased platelet aggregation response in patients with acute coronary syndrome?
Increased mean platelet volume does not correlate with hyperreactive platelets in patients with acute coronary syndrome.
Navya et al. (2023) studied this question.
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