Why the study?
Mean platelet volume has been proposed as an indicator of platelet reactivity in acute coronary syndrome, but its predictive value and response to different antiplatelet agents needed evaluation.
Does high mean platelet volume predict major adverse cardiovascular events in patients with acute coronary syndrome?
Population
1094 patients with ACS and 472 patients without ACS
Comparison
High MPV (> 9.0 fl) vs medium MPV (7.9-9.0 fl) vs low MPV (< 7.9 fl)
Design
Observational cohort study
Follow-up
Average 2.4 years
Authors
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MPV may signal elevated MACE risk in ACS; hypothesis-generating and requires prospective validation before clinical adoption.
Does high mean platelet volume predict major adverse cardiovascular events in patients with acute coronary syndrome?
Chang et al. (2019) studied this question.
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