September 1, 2009Archives of Pathology & Laboratory Medicine
Increased mean platelet volume in patients with acute coronary syndromes.
Why the study?
Does mean platelet volume (MPV) predict the diagnosis of acute coronary syndromes in adult patients presenting with chest pain?
Population
2,304 adult patients consecutively admitted during a 1-year period to the emergency department for chest…
Comparison
Mean platelet volume (MPV) measurement vs Non-ACS patients with normal cardiac troponin T…
Design
Cohort
Authors
Discussion
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Member takes
Implication
MPV was associated with ACS in chest pain; leaves open its diagnostic utility pending prospective validation.
Structured PICO
Does mean platelet volume (MPV) predict the diagnosis of acute coronary syndromes in adult patients presenting with chest pain?
P
Population
2,304 adult patients consecutively admitted during a 1-year period to the emergency department for chest pain suggestive of acute coronary syndromes (ACS).
I
Intervention
Mean platelet volume (MPV) measurement
C
Comparator
Non-ACS patients with normal cardiac troponin T levels
O
Outcome
Diagnosis of acute coronary syndromes (ACS)surrogate
Mean platelet volume is significantly elevated in patients with acute coronary syndromes and may serve as a simple, inexpensive adjunctive rule-out test in the emergency department.
Cite This Study
Lippi et al. (2009) studied this question.