Key result
Mean platelet volume was significantly higher in patients with acute coronary syndromes compared to non-ACS patients (8.3 fL vs 7.3 fL), yielding an AUC of 0.868 for diagnostic accuracy.
Why the study?
Does mean platelet volume (MPV) accurately diagnose acute coronary syndromes in adult patients presenting with acute chest pain at the emergency room?
Population
150 adult patients presenting with acute chest pain at the emergency room of the Philippine Heart Center…
Comparison
Mean platelet volume measurement via complete… vs Clinical diagnosis of ACS versus non-ACS
Design
Cross-sectional, All of the hospital staff involved in the study, including…
Authors
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MPV may aid ACS diagnosis where troponin is unavailable; leaves open incremental value and requires prospective validation before practice change.
Cross-Sectional (n=150)
Blinded
No
Does mean platelet volume (MPV) accurately diagnose acute coronary syndromes in adult patients presenting with acute chest pain at the emergency room?
Effect estimate: AUC 0.868 (95% CI 0.812-0.924)
p-value: p=<0.0001
Mean platelet volume is significantly elevated in patients with acute coronary syndromes, and a cut-off of 8.4 fL is highly specific for its diagnosis in emergency room patients with acute chest pain.
Abubakar et al. (2016) conducted a cross-sectional in Acute Coronary Syndromes (n=150). Mean Platelet Volume (MPV) vs. Non-ACS patients was evaluated on Diagnostic accuracy of Mean Platelet Volume for Acute Coronary Syndromes (Area Under the Curve) (AUC 0.868, 95% CI 0.812-0.924, p=<0.0001). Mean platelet volume was significantly higher in patients with acute coronary syndromes compared to non-ACS patients (8.3 fL vs 7.3 fL), yielding an AUC of 0.868 for diagnostic accuracy.
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