Key result
Acute coronary syndrome was associated with significantly higher mean platelet volume (9.6 vs 8.1 fL) and platelet distribution width compared to healthy controls.
Why the study?
Are platelet indices (MPV, PDW) elevated in patients with acute coronary syndrome compared to healthy controls?
Population
39 males with acute coronary syndrome presenting with altered CRP and CK-MB, median age 69, and 44 healthy…
Design
Case-control
Authors
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Elevated MPV/PDW may complement ACS thrombotic risk assessment; leaves open incremental prognostic value pending prospective validation.
Case-Control (n=83)
No
Are platelet indices (MPV, PDW) elevated in patients with acute coronary syndrome compared to healthy controls?
Absolute Event Rate: 9.6% vs 8.1%
p-value: p=<0.01
Platelet indices such as MPV and PDW are significantly elevated in patients with acute coronary syndrome and may serve as complementary markers for thrombotic risk.
Costa et al. (2015) conducted a case-control in Acute Coronary Syndrome (n=83). Acute Coronary Syndrome vs. Healthy controls was evaluated on Mean Platelet Volume (MPV) (p=<0.01). Acute coronary syndrome was associated with significantly higher mean platelet volume (9.6 vs 8.1 fL) and platelet distribution width compared to healthy controls.
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