Why the study?
Does 60 minutes of aerobic ergometric exercise alter cardiac function and blood pressure in healthy untrained volunteers?
Does 60 minutes of aerobic ergometric exercise alter cardiac function and blood pressure in healthy untrained volunteers?
Prolonged aerobic exercise in healthy untrained subjects leads to decreased blood pressure, left ventricular filling, and contractility, suggesting cardiac fatigue.
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May indicate post-exercise cardiac fatigue in untrained volunteers; hypothesis-generating and leaves open relevance to athletes or patients.
We studied 11 healthy untrained volunteers (aged 28.9 +/- 4.6 years) during 60 minutes of aerobic ergometric exercise with constant heart rates of 130 to 140 beats/minute. We found a continuous and significant decrease in systolic and diastolic pressure from 175 +/- 18/77 +/- 7 mmHg in the 5th minute to 144 +/- 14/68 +/- 6 mmHg in the 60th minute of exercise. Cardiac function and structure were assessed by M-mode echocardiography before exercise, after 5 minutes and after 60 minutes of exercise at comparable heart rates. The results demonstrated significant decreases in cardiac output, ejection fraction, and diastolic posterior wall velocity and an increase in total peripheral resistance after 60 minutes of exercise. We conclude that the decrease in blood pressure during long-term aerobic exercise in healthy untrained subjects might be at least influenced by a decrease in left ventricular filling and contractility, possibly indicating cardiac fatigue.
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Ketelhut et al. (1992) studied this question.
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