Why the study?
Does acute myocardial infarction alter platelet sensitivity to platelet activating factor (PAF) and PGI2 ex vivo?
Population
Patients with acute myocardial infarction, patients with acute bacterial pneumonia, and patients with acute…
Design
Other
Follow-up
up to 14 days
Authors
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May heighten early thrombotic risk after AMI; leaves open whether PAF or PGI2 pathways merit targeted trials.
Does acute myocardial infarction alter platelet sensitivity to platelet activating factor (PAF) and PGI2 ex vivo?
Acute myocardial infarction is associated with a transient increase in platelet sensitivity to PAF and a prolonged decrease in sensitivity to PGI2 inhibition.
Tselepis et al. (1991) studied this question.
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