January 1, 1991European Journal of Cardio-Thoracic Surgery

Is lung biopsy useful for surgical decision making in congenital heart disease?

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Why the study?

Does lung biopsy grading of pulmonary vascular disease predict surgical outcomes in patients with congenital heart disease?

Structured PICO

Does lung biopsy grading of pulmonary vascular disease predict surgical outcomes in patients with congenital heart disease?

Population

60 patients with congenital heart disease (CHD), age range 3 months-45 years (median 2 years), including 25 with AV septal defect, 14 with VSD, 7 with TGA + VSD, 3 with ASD, 2 with PDA, and 9 with other malformations.

Intervention

Lung biopsy with histological scoring (0-4) according to a modified Heath-Edwards classification to assess pulmonary vascular disease (PVD).

Outcome

Surgical outcomes (early and late deaths) and their association with histological PVD grading and pulmonary vascular resistance.hard clinical

Lung biopsy grading of pulmonary vascular disease identifies patients with congenital heart disease at high risk of fatal surgical outcomes, as most postoperative deaths occurred in those with irreversible lesions.

Discussion

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Implication

Lung biopsy may stratify mortality risk in congenital heart surgery; leaves open whether it should guide decisions.

Cite This Study

Frescura et al. (1991) studied this question.

synapsesocial.com/papers/6a7641863025cdd732bcb671 https://doi.org/10.1016/1010-7940(91)90209-3

Topics

Congenital heart disease adults

View Full Paper

Ask AI

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Is lung biopsy useful for surgical decision making in congenital heart disease?

Structured PICO

Discussion

Implication

Cite This Study

Topics

Is lung biopsy useful for surgical decision making in congenital heart disease?

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider