Why the study?
Does heavy alcohol intake alter myocardial enzyme activity and myocardial function in patients with dilated cardiomyopathy?
Population
38 patients with dilated cardiomyopathy diagnosed by cardiac catheterisation and left ventricular biopsy
Comparison
Heavy drinking vs Abstinent or light drinking
Design
Cross-sectional
Authors
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Heavy alcohol intake associated with raised myocardial enzymes in dilated cardiomyopathy; supports distinct alcoholic cardiomyopathy but leaves causality and practice change open.
Does heavy alcohol intake alter myocardial enzyme activity and myocardial function in patients with dilated cardiomyopathy?
Heavy alcohol intake in patients with dilated cardiomyopathy is associated with raised myocardial tissue enzymes, supporting the concept of alcoholic heart muscle disease as a distinct entity.
Richardson et al. (1986) studied this question.