August 1, 1995Hepatology
Relationship between cardiomyopathy and liver disease in chronic alcoholism
Population
110 men, including 30 alcoholic men with cardiomyopathy, 30 alcoholic men without cardiomyopathy, 20…
Design
Cross-sectional
Authors
Discussion
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Implication
Higher cirrhosis prevalence in alcoholic cardiomyopathy challenges common perception; hypothesis-generating and requires prospective confirmation before changing practice.
Structured PICO
P
Population
110 men, including 30 alcoholic men with cardiomyopathy, 30 alcoholic men without cardiomyopathy (left ventricular ejection fraction > 55%), 20 actively drinking alcoholics with cirrhosis, 15 abstaining alcoholics with cirrhosis, and 15 nonalcoholics with cirrhosis of other etiologies.
O
Outcome
Prevalence of cirrhosis and echocardiographic measures of cardiac performance (ejection fraction, shortening fraction, end-diastolic diameter, and left ventricular mass)surrogate
Contrary to common clinical perception, there is a positive correlation between alcoholic cardiomyopathy and cirrhosis, with actively drinking alcoholics showing impaired cardiac performance.
Cite This Study
Estruch et al. (1995) studied this question.