Key result
Chronic alcohol consumption was associated with increased epicardial adipose tissue, myocardial fibrosis, myofiber degeneration, and elevated cardiac iron levels compared to non-alcoholic controls.
Why the study?
Does chronic alcohol consumption cause subclinical histopathological changes and increased iron deposition in the myocardium?
Population
40 consecutive patients who were chronic alcoholics and 10 age-matched controls (no history of alcohol intake)
Comparison
Chronic alcohol consumption vs Age-matched controls with no history of alcohol…
Design
Cohort
Authors
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May indicate early myocardial injury in chronic alcohol users; hypothesis-generating and requires prospective confirmation before clinical adoption.
Case-Control (n=50)
Does chronic alcohol consumption cause subclinical histopathological changes and increased iron deposition in the myocardium?
Chronic alcohol consumption is associated with subclinical myocardial changes and increased cardiac iron content, which may precede clinical cardiac dysfunction.
Vaideeswar et al. (2014) conducted a case-control in Chronic alcoholism (n=50). Chronic alcohol consumption vs. No history of alcohol intake was evaluated on Cardiac histopathological changes and iron levels. Chronic alcohol consumption was associated with increased epicardial adipose tissue, myocardial fibrosis, myofiber degeneration, and elevated cardiac iron levels compared to non-alcoholic controls.
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