Key result
Excessive alcohol intake linked to unexplained cardiac hypertrophy and fibrosis, with ~15% fatal myocardial disease.
Population
97 deceased patients with a history of excessive alcohol intake prior to death
Design
Case_series
Authors
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May prompt alcohol history review in unexplained hypertrophy; leaves open causality and prevalence pending controlled studies.
Observational (n=97)
Chronic excessive alcohol intake is associated with significant post-mortem cardiac structural changes, including hypertrophy and fibrosis, which can lead to fatal myocardial disease.
Schenk et al. (2008) conducted an observational in Chronic alcoholism (n=97). Excessive alcohol intake was evaluated on Death from clinically obvious myocardial disease. Excessive alcohol intake was associated with unexplained cardiac hypertrophy and fibrosis in a majority of patients, with 15% dying from clinically obvious myocardial disease.
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