Why the study?
Does rhythm control with amiodarone improve cardiovascular outcomes compared to rate control in patients with atrial fibrillation, and is this modulated by left ventricular dysfunction?
Does rhythm control with amiodarone improve cardiovascular outcomes compared to rate control in patients with atrial fibrillation, and is this modulated by left ventricular dysfunction?
Rhythm control with amiodarone has comparable hospitalization and mortality rates to rate control in atrial fibrillation patients, regardless of the presence of severe left ventricular dysfunction.
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Amiodarone yields similar mortality and hospitalization rates to rate control in AF; confirms no outcome benefit regardless of severe LV dysfunction.
Cadrin‐Tourigny et al. (2014) studied this question.
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