Why the study?
Does fluorescein angiography reveal retinal vascular changes in pregnancies complicated by severe pre-eclamptic toxemia versus chronic hypertension?
Does fluorescein angiography reveal retinal vascular changes in pregnancies complicated by severe pre-eclamptic toxemia versus chronic hypertension?
Fluorescein angiography indicates that vascular changes in pre-eclamptic toxemia are choroidal rather than retinal, distinguishing it from chronic hypertension in pregnancy.
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Fluorescein angiography may differentiate pre-eclamptic toxemia from chronic hypertension; supports choroidal predominance but leaves open confirmation in larger cohorts.
A retrospective study in two university hospitals investigating retinal changes in pregnancies complicated by hypertension, seldom revealed retinal vascular changes in pre-eclamptic toxemia. Fluorescein angiography was performed on 16 severe pre-eclamptic toxemias and 14 chronic hypertension pregnancies. Normal caliber retinal vessels and normal filling time, with no subretinal or subepithelium leakage, was found in all pre-eclamptic toxemic patients. Four out of the 14 chronic hypertensive patients showed signs of mild hypertensive retinopathy. A review of the literature on fluorescein angiography in pregnancy showed that vascular changes in pre-eclamptic toxemia are choroidal rather than retinal.
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Schreyer et al. (1991) studied this question.
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