Left ventricular mass in normotensive subjects with autosomal dominant polycystic kidney disease: FIG

Autosomal dominant polycystic kidney disease increases the risk of premature cardiovascular disease and sudden death.'One possible mechanism may be left ventricular hypertrophy, which exacerbates cardiac risk in patients with other types of disease.We assessed whether disproportionate cardiac hypertrophy occurs in polycystic kidney disease. Subjects, methods, and resultsAsymptomatic, untreated subjects with normal renal function and no history of hypertension were selected from our polycystic register.Fourteen out of 23 eligible white subjects were recruited (10 women and four men, mean age 32 (SD 12) years (range 16- 55), mean supine blood pressure 122/76 mm Hg (range