Why the study?
Is the extent of late gadolinium enhancement associated with left ventricular diastolic function in patients with hypertrophic cardiomyopathy?
Population
47 patients with hypertrophic cardiomyopathy, mean age 53+/-14, 35 males, 14 with LV outflow tract…
Design
Cross-sectional
Authors
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May link LGE to diastolic dysfunction severity in HCM; hypothesis-generating and needs prospective validation.
Is the extent of late gadolinium enhancement associated with left ventricular diastolic function in patients with hypertrophic cardiomyopathy?
In patients with hypertrophic cardiomyopathy, the extent of late gadolinium enhancement on CMR correlates with left atrial volume index, suggesting myocardial scarring contributes to chronic diastolic dysfunction.
Choi et al. (2008) studied this question.
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