Diagnostic accuracy of left ventricular longitudinal function by speckle tracking echocardiography to predict significant coronary artery stenosis. A systematic review
Why the study?
Does left ventricular longitudinal function by speckle tracking echocardiography accurately predict significant coronary artery stenosis in patients with suspected cardiac ischemic chest pain?
Population
781 patients with chest pain suspected to be of cardiac ischemic origin, pooled from 6 studies. 397 had…
Comparison
Left ventricular longitudinal function… vs Coronary angiography
Design
Systematic_review
Authors
Discussion
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Member takes
Implication
GLS by STE shows only modest accuracy for CAD in chest pain; leaves open larger prospective validation of regional and stress protocols.
Structured PICO
Does left ventricular longitudinal function by speckle tracking echocardiography accurately predict significant coronary artery stenosis in patients with suspected cardiac ischemic chest pain?
P
Population
781 patients with chest pain suspected to be of cardiac ischemic origin, pooled from 6 studies. 397 (60%) had significant coronary artery stenosis (CAD+).
I
Intervention
Left ventricular longitudinal function assessment by speckle tracking echocardiography (STE), specifically global longitudinal strain (GLS)
C
Comparator
Coronary angiography (reference standard for verifying CAD+ vs CAD-)
O
Outcome
Diagnostic accuracy (AUC, sensitivity, specificity) for predicting significant coronary artery stenosissurrogate
Global longitudinal strain by speckle tracking echocardiography at rest has only modest diagnostic accuracy for predicting significant coronary artery stenosis in patients presenting with chest pain.
Cite This Study
Norum et al. (2015) studied this question.