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An investigation concerning the association of the leucocytecotyledon reaction and the expulsion of the placenta is described. The in vitro reaction does not appear to be individual-specific. It is thus possible to determine the activity of the leucocytes against a cotyledon before parturition. The leucocytes of cows which will develop a retained placenta have lowered activity against the chemotactic stimulus of a cotyledon; this reduced activity of the leucocytes can be observed some days before parturition.
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J. W. Gunnink (1984) studied this question.
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