Riociguat, a soluble guanylate cyclase stimulator, ameliorates right ventricular contraction in pulmonary arterial hypertension

Figures

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  Fig. 1.. Analysis of covariance revealed no significant differences in TAPSE (a), RV S’ (b), or RVFAC (c) before (blue line) or after (red line) riociguat administration, after adjustment for PASP. In contrast, RVGLS was significantly improved after riociguat administration (d). PASP, pulmonary arterial systolic pressure; TAPSE, tricuspid annular plane systolic excursion; RVFAC, right ventricular fractional area change; RVGLS, right ventricular global longitudinal strain.