What question did this study set out to answer?

To evaluate the effectiveness of a pharmacist-managed therapeutic conversion program compared with usual care for switching statin therapy after atorvastatin removal from a clinic formulary.

April 30, 2008Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy

Switching Statin Therapy Using a Pharmacist‐Managed Therapeutic Conversion Program versus Usual Care Conversion Among Indigent Patients

View Full Paper

Ask AI

Bookmark

Authors

AMAmy MillerUniversity School LHLaura HansenWestern New England University JSJoseph J. SaseenPreventive Cardiology

Discussion

Member takes

Implication

Prospective cohort study shows superior cholesterol control with pharmacist-managed conversion in indigent patients, indicating benefits of proactive pharmacy involvement.

Key Points

To evaluate the effectiveness of a pharmacist-managed therapeutic conversion program compared with usual care for switching statin therapy after atorvastatin removal from a clinic formulary.
Prospective cohort study of 117 ambulatory care patients with dyslipidemia previously taking atorvastatin in a university-based health system.
The intervention group (N=30) received pharmacist-managed therapeutic conversion to simvastatin, rosuvastatin, or ezetimibe-simvastatin using a goal-directed algorithm.
The usual care group (N=87) underwent physician-led switching guided by an optional equipotency algorithm.
Mean low-density lipoprotein (LDL) levels changed from 86.7 to 82.3 mg/dl (p=0.44) in the pharmacist group versus 78.3 to 85.2 mg/dl (p=0.01) in the usual care group.
LDL goal attainment increased from 80% to 97% after conversion in the pharmacist-managed group (p=0.04), whereas it dropped from 90% to 75% in the usual care group (p=0.01).

Cite This Study

Miller et al. (2008) studied this question.

synapsesocial.com/papers/6a767d0d5ae5d82e5595c736 https://doi.org/10.1592/phco.28.5.553

View Full Paper

Ask AI

Bookmark

Implication

Prospective cohort study shows superior cholesterol control with pharmacist-managed conversion in indigent patients, indicating benefits of proactive pharmacy involvement.

Switching Statin Therapy Using a Pharmacist‐Managed Therapeutic Conversion Program versus Usual Care Conversion Among Indigent Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Switching Statin Therapy Using a Pharmacist‐Managed Therapeutic Conversion Program versus Usual Care Conversion Among Indigent Patients

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider