Why the study?
Does telmisartan reduce blood pressure in patients with mild to moderate hypertension compared to enalapril or placebo?
Population
207 patients with mild to moderate hypertension (diastolic blood pressure [DBP] 100 to 114 mmHg)
Comparison
Telmisartan 40, 80, or 120 mg once-daily for 28… vs Enalapril 20 mg once-daily or matching placebo…
Design
RCT, randomized, parallel-group, double-blind, double-dummy, placebo-controlled
Follow-up
28 days
Authors
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Supports telmisartan as an alternative to enalapril for mild-moderate hypertension; confirms ARBs' comparable efficacy in RCTs.
Does telmisartan reduce blood pressure in patients with mild to moderate hypertension compared to enalapril or placebo?
Telmisartan provides significant blood pressure reduction comparable to enalapril in patients with mild to moderate hypertension, with a placebo-like tolerability profile.
Smith et al. (2000) studied this question.
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