Why the study?
Is long-term outpatient anticoagulant therapy safe and what is the incidence of bleeding complications?
Population
978 outpatients at the Henry Ford Hospital treated with long-term anticoagulants for at least three months.
Design
Cohort
Follow-up
1 year review period (August 1961 to August 1962)
Authors
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Low major bleeding rates support outpatient anticoagulation feasibility; leaves open randomized confirmation of net benefit.
Is long-term outpatient anticoagulant therapy safe and what is the incidence of bleeding complications?
Long-term outpatient anticoagulant therapy is practical and safe, with a low 1.5% incidence of major hemorrhage.
Mosley et al. (1963) studied this question.
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