Why the study?
Does batroxobin-modified TEG improve the detection of eptifibatide-induced platelet inhibition compared to conventional kaolin TEG in whole blood from healthy volunteers?
Population
Whole blood from healthy volunteers
Comparison
Batroxobin-modified thrombelastography on… vs Conventional kaolin TEG on citrated blood…
Design
Preclinical
Authors
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May enhance preclinical detection of GPIIb/IIIa inhibition; leaves open human translation pending clinical studies.
Does batroxobin-modified TEG improve the detection of eptifibatide-induced platelet inhibition compared to conventional kaolin TEG in whole blood from healthy volunteers?
Batroxobin-modified TEG is a more sensitive method than conventional kaolin TEG for monitoring the antiplatelet effects of eptifibatide at clinical concentrations.
Katori et al. (2004) studied this question.
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