Why the study?
Does preoperative clopidogrel increase the need for reexploration secondary to bleeding in patients undergoing coronary artery bypass graft surgery?
Does preoperative clopidogrel increase the need for reexploration secondary to bleeding in patients undergoing coronary artery bypass graft surgery?
Preoperative clopidogrel use before CABG significantly increases the risk of severe bleeding requiring surgical reexploration and blood product transfusions.
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Clopidogrel exposure was associated with higher reexploration rates after CABG; hypothesis-generating and should not yet change practice pending randomized trials.
Yende et al. (2001) studied this question.
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