Why the study?
Does clopidogrel administration prior to CABG surgery increase the risk of haemostatic re-operation and transfusion requirements in patients undergoing isolated CABG?
Does clopidogrel administration prior to CABG surgery increase the risk of haemostatic re-operation and transfusion requirements in patients undergoing isolated CABG?
Pre-operative clopidogrel exposure significantly increases the risk of bleeding complications and transfusion requirements in patients undergoing CABG surgery.
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May warrant delaying CABG after clopidogrel cessation; leaves open optimal timing and causal confirmation in RCTs.
Kapetanakis et al. (2005) studied this question.
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