Population
280 individuals older than 45 years, equally divided between coronary artery disease cases and controls and…
Design
Case-control
Authors
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Heterogeneous carotid IMT effects caution against single-segment reliance; leaves open whether multi-segment protocols refine risk assessment in observational cohorts.
Risk factors have heterogeneous effects on intimal-medial thickness across different segments of the carotid artery, suggesting that single-segment measurements may not accurately reflect overall atherosclerotic burden or risk factor associations.
Espeland et al. (1999) studied this question.
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