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July 14, 2019Evidence-based Complementary and Alternative MedicineOpen Access

Effects of 12-Week Supplementation of a Polyherbal Formulation in Old Adults with Prehypertension/Hypertension: A Randomized, Double-Blind, Placebo-Controlled Trial

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Why the study?

Uncontrolled blood pressure is common in older adults and leads to mortality and disability, motivating the hypothesis that plant extract-based antioxidants may benefit prehypertension or hypertension.

Does a 12-week supplementation of a polyherbal formulation (HyperBalance) reduce blood pressure and improve symptoms in older adults with prehypertension or hypertension?

Comparison

HyperBalance capsules vs placebo

Design

Randomized, double-blind, placebo-controlled trial

Follow-up

12 weeks

Authors

STShen TianShanghai Jiao Tong UniversityGXGuoqiang XingNorth Sichuan Medical UniversityJZJingfen ZhuShanghai Jiao Tong University

Discussion

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Implication

Polyherbal antioxidant supplementation may lower BP in older adults with prehypertension; leaves open clinical adoption pending larger outcome trials.

Structured PICO

Does a 12-week supplementation of a polyherbal formulation (HyperBalance) reduce blood pressure and improve symptoms in older adults with prehypertension or hypertension?

P
Population
100 healthy older adults with prehypertension (SBP 130-139 and DBP 85-89 mmHg) or hypertension (≥140/90 mmHg) at a single center in Shanghai, China.
I
Intervention
HyperBalance capsules (polyherbal formulation) for 12 weeks
C
Comparator
Placebo for 12 weeks
O
Outcome
Blood pressure (systolic and diastolic) and severity scores of hypertension treatment-related symptoms (dizziness, headache, ringing/buzzing in ears, rapid heart rate, and chest tightness) at 12 weekssurrogate

A 12-week supplementation with a polyherbal formulation significantly reduced blood pressure and improved treatment-related symptoms in older adults with prehypertension or hypertension.

Cite This Study

Tian et al. (2019) studied this question.

synapsesocial.com/papers/6a7693fd5f7f0b63027d1cdfhttps://doi.org/10.1155/2019/7056872
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Also Consider

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