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January 1, 2011Indian Journal of Community MedicineOpen Access

Non-pharmacological interventions in hypertension: A community-based cross-over randomized controlled trial

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Key result

Physical exercise significantly reduced systolic blood pressure more effectively than salt reduction (MD -2.76 mmHg) and yoga in young pre-hypertensive and hypertensive adults.

Why the study?

Do physical exercise, salt intake reduction, and yoga reduce blood pressure in young pre-hypertensive and hypertensive adults?

Population

98 prehypertensive and hypertensive young adults from an urban service area in Puducherry, India.

Comparison

Physical exercise, salt intake reduction, or… vs Control group for 8 weeks.

Design

RCT, Randomly allotted into a group that he/she had not belonged to in the…

Follow-up

8 weeks

Authors

MSM. B. SoudarssananeJawaharlal Institute of Post Graduate Medical Education and ResearchHSHema SubramanianNarayana HealthDTD ThiruselvakumarJawaharlal Institute of Post Graduate Medical Education and Research

Discussion

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Overview

Exercise should be prioritized over salt reduction or yoga for BP reduction in young prehypertensives; extends comparative RCT evidence for nonpharmacological strategies.

Study Design

Type

RCT (n=98)

Randomization

Cross-over randomization

Multicenter

No

Structured PICO

Do physical exercise, salt intake reduction, and yoga reduce blood pressure in young pre-hypertensive and hypertensive adults?

P
Population
98 prehypertensive and hypertensive young adults (mean age 23.5 years) were randomized in a cross-over trial to evaluate physical exercise, salt reduction, and yoga over 8 weeks.
I
Intervention
Physical exercise (brisk walking 50-60 mins, 3-4 days/week), salt intake reduction (by half of previous intake), or yoga (30-45 mins/day, 5 days/week) for 8 weeks.
C
Comparator
Control group (no specific intervention) for 8 weeks.
O
Outcome
Reduction in systolic and diastolic blood pressure after 8 weeks of intervention.surrogate

Main Result

Mean Difference: -2.76 (95% CI -4.67–-0.85)

Absolute Event Rate: 5.4% vs 2.6%

p-value: p=0.003

Physical exercise, salt reduction, and yoga are effective non-pharmacological methods for reducing blood pressure in young pre-hypertensive and hypertensive adults, with physical exercise being the most effective.

Limitations

  • Possibility of the influence of knowledge from the earlier study as all control group members had belonged to interventional groups in the earlier study
  • Subjective BP variation with time or the influence of lifestyle changes in the interventional groups on the cohort of the control group

Cite This Study

Soudarssanane et al. (2011) conducted an RCT in Prehypertension and hypertension (n=98). Physical exercise vs. Salt intake reduction was evaluated on Difference in systolic blood pressure reduction (MD -2.76, 95% CI -4.67 to -0.85, p=0.003). Physical exercise significantly reduced systolic blood pressure more effectively than salt reduction (MD -2.76 mmHg) and yoga in young pre-hypertensive and hypertensive adults.

synapsesocial.com/papers/6a7faba4812a481b9a5f264fhttps://doi.org/10.4103/0970-0218.86519
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nonpharmacologic Control of Essential Hypertension in Man: A Critical Review of the Experimental Literature1978 · 66 citations
  2. 2Effects of Comprehensive Lifestyle Modification on Blood Pressure Control2003 · 1,340 citations
  3. 3Trends in Blood Pressure Among Children and Adolescents2004 · 889 citations
  4. 4Systematic review of long term effects of advice to reduce dietary salt in adults2002 · 301 citations
  5. 5Long term effects of dietary sodium reduction on cardiovascular disease outcomes: observational follow-up of the trials of hypertension prevention (TOHP)2007 · 1,188 citations