Key result
DASH diet lowers systolic BP ~7 mm Hg versus usual care and other nonpharmacologic interventions.
Why the study?
Although nonpharmacologic lifestyle interventions can lower blood pressure, it remained unclear which intervention is the most efficacious.
Do nonpharmacologic interventions reduce blood pressure in adults with prehypertension to established hypertension?
Population
14 923 adults with prehypertension to established hypertension across 120 articles
Comparison
22 nonpharmacologic interventions vs usual care and each other
Design
Bayesian network meta-analysis
Follow-up
Median 12 weeks
Authors
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Supports DASH as first-line nonpharmacologic therapy for hypertension; confirms superiority over alternatives in Level 1 evidence synthesis.
Meta-Analysis (n=14,923)
Do nonpharmacologic interventions reduce blood pressure in adults with prehypertension to established hypertension?
Effect estimate: WMD 6.97 mm Hg (95% CI 4.50-9.47)
The DASH diet is the most effective nonpharmacologic intervention for lowering blood pressure in adults with prehypertension to established hypertension.
Fu et al. (2020) conducted a meta-analysis in Prehypertension to established hypertension (n=14,923). Dietary Approach to Stop Hypertension (DASH) vs. Usual care and other nonpharmacologic interventions was evaluated on Lowering systolic BP (WMD 6.97 mm Hg, 95% CI 4.50-9.47). The Dietary Approach to Stop Hypertension (DASH) was superior to usual care and all other nonpharmacologic interventions in lowering systolic BP (WMD 6.97 mm Hg; 95% CrI 4.50-9.47).
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