Why the study?
Does intermittent hemodialysis or continuous renal replacement therapy enhance the elimination of dabigatran in patients with severe bleeding or requiring emergent surgery?
Population
7 patients requiring enhanced elimination of dabigatran
Design
Case_series
Authors
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IHD may enhance dabigatran elimination more than CRRT in case reports; leaves open optimal RRT strategy for bleeding or surgery.
Does intermittent hemodialysis or continuous renal replacement therapy enhance the elimination of dabigatran in patients with severe bleeding or requiring emergent surgery?
Intermittent hemodialysis enhances the elimination of dabigatran more efficiently than continuous renal replacement therapy, though clinical decisions must be individualized.
Bouchard et al. (2015) studied this question.
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