Why the study?
Venous thromboembolism risk persists after hospitalization in surgical patients, yet post-discharge chemoprophylaxis regimens are not common.
Does extended-duration (post-hospital discharge) VTE chemoprophylaxis reduce the incidence of VTE in high-risk surgery patients?
Comparison
Extended-duration VTE chemoprophylaxis vs no extended-duration chemoprophylaxis
Design
Systematic review
Authors
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Supports extended post-discharge VTE prophylaxis in high-risk surgical patients; confirms safety and efficacy in meta-analysis.
Does extended-duration (post-hospital discharge) VTE chemoprophylaxis reduce the incidence of VTE in high-risk surgery patients?
Extended-duration VTE chemoprophylaxis in high-risk surgical patients significantly decreases the incidence of VTE without increasing the risk of bleeding events.
Shaikh et al. (2020) studied this question.
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