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May 1, 1984Journal of Pharmacy and Pharmacology

Comparison between in-vivo and in-vitro tissue-to-plasma unbound concentration ratios (Kp,f) of quinidine in rats

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Authors

HHHideyoshi HarashimaHokkaido University of Science YSYuichi SugiyamaKanazawa University YSYasufumi SawadaThe University of Tokyo

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Implication

May inform unbound tissue distribution modeling for weak bases; leaves open accurate in vivo translation without further validation.

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Cite This Study

Harashima et al. (1984) studied this question.

synapsesocial.com/papers/6a76aaa4a7498e5110adf603 https://doi.org/10.1111/j.2042-7158.1984.tb04390.x

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Also Consider

Synapse has enriched one closely related paper. Consider it for comparative context:

1Quantitative Determination of Quinidine in Plasma1963 · 175 citations