Why the study?
Which health-related quality of life measure is most responsive to clinical change in patients with heart failure?
Population
298 subjects with moderate to severe heart failure symptoms, average age 60 years, 75% male.
Design
Cohort
Follow-up
6 weeks
Authors
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KCCQ may be preferred for detecting short-term HF changes; hypothesis-generating for trial endpoints and monitoring.
Which health-related quality of life measure is most responsive to clinical change in patients with heart failure?
The disease-specific KCCQ is more responsive to clinical change over a 6-week period than generic HRQL measures in patients with heart failure.
Eurich et al. (2006) studied this question.
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