Population
Bovine endothelial cells (FBHE), cell culture, and oocytes
Design
Preclinical
Authors
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May guide ECE-1 inhibitor development for endothelin disorders; leaves open human cardiovascular outcomes.
The study successfully isolated and characterized the complete cDNAs of bovine and human endothelin converting enzyme (ECE-1), confirming its identity as a functional metalloprotease.
Schmidt et al. (1994) studied this question.
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