October 16, 1996JAMA
Epidemiologic Assessment of the Role of Blood Pressure in Stroke
Why the study?
Does hypertension increase the risk of atherothrombotic brain infarction compared to normotension?
Population
Individuals assessed prospectively for the development of atherothrombotic brain infarction
Comparison
Hypertension vs Normotension
Design
Cohort
Authors
Discussion
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Member takes
Implication
May inform stroke risk stratification; leaves open whether treatment reduces atherothrombotic brain infarction incidence.
Structured PICO
Does hypertension increase the risk of atherothrombotic brain infarction compared to normotension?
P
Population
Individuals assessed prospectively for the development of atherothrombotic brain infarction
I
Intervention
Hypertension (systolic or diastolic, labile or fixed)
C
Comparator
Normotension
O
Outcome
Atherothrombotic brain infarction (ABI)hard clinical
Hypertension, particularly systolic elevation, is a potent and direct precursor to atherothrombotic brain infarction across all ages and both sexes.
Cite This Study
William B. Kannel (1996) studied this question.