December 2, 2008JAMA
Framingham Study Insights on the Hazards of Elevated Blood Pressure
Why the study?
Does elevated blood pressure increase the risk of atherothrombotic brain infarction?
Population
Participants in the Framingham Study
Comparison
Elevated blood pressure vs Normotension
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports incorporating casual hypertension into stroke risk assessment; leaves open causal effects and treatment benefits in asymptomatic adults.
Structured PICO
Does elevated blood pressure increase the risk of atherothrombotic brain infarction?
P
Population
Participants in the Framingham Study
I
Intervention
Elevated blood pressure (hypertension, including labile, fixed, systolic, or diastolic)
C
Comparator
Normotension
O
Outcome
Atherothrombotic brain infarction (ABI)hard clinical
Hypertension, particularly systolic elevation, is a potent precursor to atherothrombotic brain infarction across all ages and both sexes, challenging the notion that systolic hypertension is benign in the elderly.
Cite This Study
William B. Kannel (2008) studied this question.