Why the study?
Severe tricuspid regurgitation carries an increasing burden, but conventional surgery carries increased risk and existing interventional procedures under investigation lack comprehensive solutions.
Does a novel off-pump beating-heart tricuspid annuloplasty approach demonstrate feasibility in a preclinical porcine model?
Does a novel off-pump beating-heart tricuspid annuloplasty approach demonstrate feasibility in a preclinical porcine model?
A novel off-pump beating-heart tricuspid annuloplasty approach demonstrates early feasibility in a preclinical porcine model, supporting further development of minimally invasive hybrid procedures for severe tricuspid regurgitation.
Early porcine feasibility supports further development of off-pump tricuspid repair; leaves open human safety and efficacy.
Severe tricuspid regurgitation constitutes a growing disease burden. Conventional surgery for tricuspid valve disease has an increased risk while several interventional procedures are currently under clinical investigation, yet do not offer comprehensive solutions. We investigated a novel surgical approach for off-pump beating-heart tricuspid annuloplasty in circulating blood through a single port in the right atrium. Early feasibility results in preclinical porcine in vivo studies encourage further development of this approach, combining the proven concept of surgical annuloplasty with the benefits of minimally invasive off-pump procedures in a hybrid setting.
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Andreas et al. (2019) studied this question.
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