Why the study?
Survivors of allo-HSCT are at higher risk of cardiovascular disease, but RV systolic function and risk factors for RV dysfunction in long-term survivors treated in their youth required description.
Do long-term survivors of allogeneic haematopoietic stem-cell transplantation have impaired right ventricular function compared to healthy controls?
Do long-term survivors of allogeneic haematopoietic stem-cell transplantation have impaired right ventricular function compared to healthy controls?
Long-term survivors of allo-HSCT treated in their youth exhibit impaired right ventricular function, which is associated with progressive left ventricular dysfunction and prior anthracycline therapy.
RV dysfunction in youth allo-HSCT survivors warrants echocardiographic vigilance; observational data leaves causal mechanisms and screening protocols open.
No takes yet. Share an insight, caveat, or question.
Massey et al. (2021) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: