Why the study?
Does increased pathogen burden increase the risk of myocardial infarction or death in patients with significant CAD?
Population
890 patients with significant coronary artery disease (CAD) on angiography
Comparison
Pathogen burden vs Lower pathogen burden / absence of specific…
Design
Cohort
Follow-up
mean 3 years
Authors
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Associated with higher MI or death risk in CAD; leaves open whether pathogen reduction improves outcomes.
Does increased pathogen burden increase the risk of myocardial infarction or death in patients with significant CAD?
Increasing pathogen burden is independently associated with a higher risk of incident MI or death in patients with established CAD, regardless of CRP levels.
Zhu et al. (2001) studied this question.
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